Air:
Comodoro Arturo Merino Benítez International Airport is Santiago's national and international airport. 15 minutes from downtown through the urban highways (Costanera Norte-Vespucio Norte). The airport currently serves non-stop flights from Santiago to the United States via Miami, Dallas, Los Angeles, New York and Atlanta.

Rail:
Trains operated by Chile's national railway, Empresa de los Ferrocarriles del Estado, connect Santiago to Chillan, in the central-southern part of the country. All such trains arrive and depart from the Estación Central ("Central Station") which can be accessed by bus or subway.
The routes and coverage are from:
Santiago-San Fernando.
Santiago-Chillán.
Talca-Constitución.
Talcahuano-Hualqui.
Talcahuano-Renaico.
Victoria-Temuco.

Inter-urban buses:
Bus companies provide passenger transportation from Santiago to most areas of the country, while some also provide parcel-shipping and delivery services. There are several bus terminals in Santiago:
Terminal San Borja: located near the Metro station "Estación Central", where also depart train services to Rancagua, Talca and Chillán.
Terminal Los Heroes: located near the Metro station "Los Héroes"
Terminal La Paz: located in the municipality of Independencia, the closest Metro station is "Puente Cal y Canto"
Alameda Interchange: located near the Metro station "Universidad de Santiago", from here depart a veriety of bus services to the south of Chile.
Pajaritos Interchange: located in the same name Santiago Metro station, provides bus services to the international airport, inter-regional services to Valparaíso, Viña del Mar and several other coastal cities and towns.

Highways:
Toll road, inter-urban free flow highways connect the city's extremes, including the Vespucio Highway (which surrounds the city describing a semicircle), Autopista Central (which crosses the city in a North-South direction), and the Costanera Norte (which runs from the eastern edge, in Las Condes to the international airport and the highways to Valparaíso on the western side of the city).

Public transport:
Santiago has 37.32% of Chile's vehicles, with a total of 991,838 vehicles, 979,346 of which are motorized. 805,220 cars pass through the city, which is equivalent to 37.63% of the national and at a rate of one car for every 7 people. To support this huge number of cars there is an extensive network of streets and avenues stretching across Santiago to facilitate travel between the different communities that make up the metropolitan area.

As regards public transport, during the 1990s various governmental efforts were attempted to resolve what was considered a chaotic system in the city. There were tendered in 1994 for the first time for the routes of the yellow buses (minibuses identified with the colour). Despite this, the system had serious issues of routes overlapping, contamination and unsafety for riders, and therefore a new transport system, called Transantiago was devised. The system was launched on February 10, 2007, combining core services across the city with a local feeder routes, which have a unified system of payment through a contactless smartcard called "Tarjeta bip!". In its first months, Transantiago showed a series of errors in design and implementation, which lately have been majorly resolved by the authorities. However, a high rate of evasion of fare payment, and some frequency issues in certain areas remain as of August 2010.
Metro de Santiago carries over 2 million passengers daily through its five lines (1, 2, 4, 4A and 5), extending over 84 km and 89 stations. By the end of 2010, a new extension to the commune of Maipú will make Metro expand to more than 105 km in length. Construction of two new lines (3 and 6) was confirmed recently by president Sebastián Piñera, and is expected to be operating in 2014.
Other local transport systems include 25,000 taxis, identified by black colour cars and yellow roof. In regard to cycling, in recent years the city has tried to promote the use of bicycles with the construction of bike paths and bike lanes, but so far the number built is limited and with little connections between the routes. Most cyclists ride on the street, and the use of helmets and lights is not extended.

Metro:
With 101 stations currently in operation and 16 under construction, the Santiago Metro is South America's most extensive metro system. The system has five operating lines and carries around 2,400,000 passengers per day. Two underground lines (Line 4 and 4A) and an extension of Line 2 were inaugurated during late 2005 and beginning of 2006. Further extensions are currently underway on Lines 1 and 5. An announcement of plans for a new line was made by President Bachelet. The South Express Line, Line 6, will be finished by 2014, adding 12 stations to the network and approximately 15 km of track.

Commuter Rail:
The company Trenes Metropolitanos S.A. provides suburban rail service under the brandname of Metrotren. There is only one southbound route, serving 18 stations between the Central Station of Santiago at Alameda and San Fernando, via Paine and Graneros. The electrified service expands over 138 km (85.75 mi). About 10 daily trains operate the full distance in each direction, with up to 30 trains between Santiago and Graneros

Bus:
Transantiago is the name for the city's public transport system. It works by combining local (feeder) bus lines, main bus lines and the Metro network. It includes an integrated fare system, which allows passengers to make bus-to-bus or bus-to-metro transfers for the price of one ticket, using a contactless smartcard. Fares cannot be paid in cash, and if the card have not enough credit, must be recharged before a trip.

Taxi:
Taxicabs are common in Santiago and are painted black with yellow roofs and have orange license plates. So-called radiotaxis may be called up by telephone and can be any make, model, or color but should always have the orange plates. Colectivos are shared taxicabs that carry passengers along a specific route for a fixed fee. Santiago also has some illegal taxis without the orange plates indicating proper licensing. These are especially common near the airport and should generally be avoided for safety.